A case series of different courses of methotrexate-associated lymphoproliferative disease with pulmonary involvement

Lymphoproliferative Disorder (LPD) is a complication of Methotrexate (MTX) therapy. Several cases Methotrexate-Associated (MTX-LPD) have been reported. However, pulmonary lesions in MTX-LPD are rare. Image findings show various patterns. Pneumocystis pneumonia and interstitial pneumonia, which complex courses, reported MTX-treated patients with lung diseases other than MTX-LPD. Furthermore, the treatment course differs from those could vary across patients. Here in, we discuss importance an accurate diagnosis through detailed examination priority depending on severity underlying complications.